ABSTRACT
OBJECTIVE: Estimation of prevalence of Candida in the oral cavity of diabetic and non-diabetic subjects. MATERIAL AND METHODS: One hundred and three subjects of diabetes mellitus (49 Type 1 diabetes mellitus and 54 Type 2 diabetes mellitus) and one hundred non-diabetic subjects (control) were studied. RESULTS: 41(83.67%) out of 49 Type 1 diabetes mellitus, 37(68.52%) out of 54 Type 2 diabetes mellitus and 27(27%) out of 100 in non-diabetic subjects were found to carry Candida in their oral cavity. Colony Forming Unit (CFU) of Candida in the oral cavity ranking in groups was Type 1 diabetes mellitus > Type 2 diabetes mellitus > non-diabetic subjects. CONCLUSION: Colonization and carriage of Candida in the oral cavity was found to be higher in diabetic subjects than in non-diabetic subjects. However anti-diabetic therapy and glycaemic control in diabetes were found to bear no relation with carriage of Candida in the oral cavity.
Subject(s)
Candida/isolation & purification , Candidiasis, Oral/epidemiology , Diabetes Complications/epidemiology , Diabetes Mellitus, Type 1/complications , Diabetes Mellitus, Type 2/complications , Female , Humans , India/epidemiology , Male , Mouth/microbiology , PrevalenceABSTRACT
Fifty patients with insulin-dependent diabetes mellitus (IDDM) in the age group of 5-20 years were assessed for oral candidal carriage state and other related oral manifestations. The control group showed 16% Candida carrier state, whereas the IDDM group showed 92% candida carrier state. The candidal count was significantly higher in the IDDM group. Other associated oral manifestations like dry mouth, burning sensation, and painful fissures were also observed in the IDDM subjects.